Table 1 Baseline patient characteristics.
Variable | All (n = 100) | Bone-only progressors (n = 10) | Other progressors (n = 21) | p value (bone versus other) |
|---|---|---|---|---|
Hb (g/dl) | 12.9 (9.8–16) | 13.4 (11.4–14.8) | 12.6 (10.9–14.2) | 0.245 |
WBC (×10–3) | 6.2 (2.2–13.5) | 5.9 (3.2–8.8) | 6.0 (2.2–13.5) | 1.000 |
PLTs (×10−3) | 251 (94–686) | 273 (178–451) | 219 (146–582) | 0.673 |
Cr (mg/dl) | 0.8 (0.4–8) | 0.8 (0.54–1.29) | 0.73 (0.5–1.5) | 0.245 |
Ca (mg/dl) | 9.5 (7.39–11) | 9.29 (8.5–10.6) | 9.6 (8.9–10.6) | 0.695 |
B2 microglobulin (mg/l) | 2.2 (0.9–15) | 2.21 (1.06–4.41) | 2.33 (0.90–4.03) | 1.000 |
LDH (U/l) | 169 (103–325) | 160 (103–221) | 169 (110–274) | 1.000 |
Alb (g/dl) | 4.3 (3.2–5.3) | 4.2 (3.7–4.8) | 4 (3.2–4.7) | 1.000 |
IgG (mg/dl) | 1580 (358–5824) | 1550 (626–4170) | 1800 (420–5824) | 1.000 |
IgA (mg/dl) | 104 (5–4181) | 60.7 (14–1336) | 97.7 (22–1590) | 1.000 |
IgM (mg/dl) | 41.9 (4–369) | 36.4 (12–171) | 41 (4–205) | 0.420 |
Mpeak (g/dl) | 1.51 (0–4.9) | 2.67 (0.86–3.66) | 2.34 (0–4.94) | 0.700 |
κFLC (mg/l) | 21.9 (1.34–990) | 29.6 (11.5–635) | 31.8 (1.34–990) | 1.000 |
λFLC (mg/l) | 12.15 (1.08–9.88) | 11.4 (5.2–760) | 9.55 (1.08–988) | 0.700 |
FLC ratio >8 (n, %) | 33 (33.3) | 5 (50) | 11 (55) | 0.796 |
BM infiltration (%) | 20 (10–55) | 22.5 (15–40) | 35 (10–55) | 0.260 |
Heavy chain (n) | 97 | 10 | 19 | 0.266 |
IgG | 23 | 6 | 16 | |
IgA | 74 | 4 | 3 | |
Light chain only | 3 (1κ, 2λ) | 0 | 1 | |
Risk for progressiona (%) | 0.773 | |||
Low | 29 | 0 | 5 | |
Intermediate | 36 | 40 | 25 | |
High risk | 31 | 60 | 70 |
