Fig. 4: Summary chromosomal and mutational findings. | Blood Cancer Journal

Fig. 4: Summary chromosomal and mutational findings.

From: CREBBP and STAT6 co-mutation and 16p13 and 1p36 loss define the t(14;18)-negative diffuse variant of follicular lymphoma

Fig. 4: Summary chromosomal and mutational findings.

a The top panel shows the total number of mutations (shaded black) and CNVs (shaded with diagonal stripes) detected in each case, and statistical comparison of total alterations per case between the two groups (those with CREBBP and STAT6 comutations, and those without)*. The next row in green denotes tumor mutation burden as mutations/Mb. Crossed boxes represent cases without (interpretable) data. The # sign corresponds to cases with suspected aberrant somatic hypermutation. Copy number and FISH abnormalities are summarized in the red panel. Crossed boxes represent cases without (interpretable) data. The bottom panel demonstrates mutational status for all mutated genes. 0 indicates no mutations detected. 1 indicates a single mutation. 2+ indicates 2 or more different mutations within a single case. b Prevalence of the corresponding abnormality in the entire group.*Case 16 was excluded from this analysis due to absence of SNP-array data.

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