Fig. 1: The prevalence of copy number alterations and driver mutations in pPCL compared to MM.

a pPCL is enriched for adverse risk copy number alterations compared to MM17, *p < 0.05. Significant genes are labeled, with the exception of markers on chromosomes associated with hyperdiploidy. b The frequency of driver mutations in pPCL and MM, *p < 0.05 (chi-square test); +p < 0.005 (after multiple test correction).