Table 1 Comparison of pre-existing diagnoses in AL amyloidosis by race.
From: Racial disparities in patients diagnosed with light chain (AL) amyloidosis
ICD code | Pre-existing diagnosis | Black, with AL N = 691 | White, with AL N = 691 | p-value | SD |
|---|---|---|---|---|---|
D47.2 | MGUS | 21.13% | 12.88% | 4.48E−05 | 0.22 |
C90 | Multiple myeloma | 32.42% | 30.83% | 0.53 | 0.03 |
Cardiac diagnoses | |||||
I51.7 | Cardiomegaly | 28.51% | 20.55% | 0.0006 | 0.19 |
I42 | Cardiomyopathy | 37.19% | 22.58% | 2.93E−09 | 0.32 |
I49 | Other cardiac arrythmia | 30.25% | 19.68% | 5.7E−06 | 0.25 |
R06.0 | Dyspnea | 49.78% | 35.17% | 3.88E−08 | 0.30 |
R55 | Syncope and collapse | 13.46% | 9.70% | 0.03 | 0.12 |
R42 | Dizziness and giddiness | 14.33% | 14.62% | 0.88 | 0.01 |
R60 | Edema | 33.58% | 26.77% | 0.006 | 0.15 |
I50 | Heart failure | 54.85% | 33.29% | 6.85E−16 | 0.45 |
J90 | Pleural effusion | 11.43% | 11.72% | 0.87 | 0.01 |
I48 | Atrial fibrillation and flutter | 21.85% | 21.85% | 1 | 0 |
I95 | Hypotension | 21.71% | 18.67% | 0.16 | 0.08 |
Renal diagnoses | |||||
N04, | Nephrotic syndrome | 8.39% | 9.84% | 0.35 | 0.05 |
R80 | Proteinuria | 23.16% | 19.97% | 0.15 | 0.08 |
N18 | Chronic kidney disease | 43.56% | 35.02% | 0.001 | 0.18 |
Neurological diagnoses | |||||
N52.9 | Male erectile dysfunction | 7.67% | 4.34% | 0.009 | 0.14 |
M79.2 | Neuralgia and neuritis | 2.17% | 2.61% | 0.60 | 0.03 |
R20 | Disturbances of skin sensations | 13.89% | 11.00% | 0.10 | 0.09 |
G60 | Hereditary and idiopathic neuropathy | 12.59% | 10.42% | 0.21 | 0.07 |
G62 | Other and unspecified polyneuropathies | 11.72% | 11.29% | 0.80 | 0.01 |
G90 | Disorders of autonomic nervous system | 2.75% | 3.47% | 0.44 | 0.04 |
GI/Hepatic diagnoses | |||||
R13.1 | Dysphagia | 12.88% | 9.70% | 0.06 | 0.10 |
R16 | Hepatomegaly and splenomegaly | 5.79% | 5.79% | 1 | 0 |
K76 | Other diseases of liver | 13.17% | 11.00% | 0.22 | 0.07 |
R11 | Nausea and vomiting | 19.83% | 16.35% | 0.09 | 0.09 |
K59.0 | Constipation | 22.00% | 14.76% | 0.0005 | 0.19 |
R19.7 | Diarrhea | 15.63% | 17.95% | 0.25 | 0.06 |
R10 | Abdominal pain | 27.50% | 19.25% | 0.0003 | 0.20 |
Other diagnoses | |||||
R53 | Malaise and fatigue | 30.83% | 30.39% | 0.86 | 0.01 |
G56.0 | Carpal Tunnel Syndrome | 11.14% | 7.24% | 0.01 | 0.14 |
D69 | Purpura | 15.20% | 14.47% | 0.71 | 0.02 |
Q38 | Macroglossia | 2.32% | 1.45% | 0.24 | 0.06 |
