Table 2 Cox regression-factors affecting OS and NRM in all the patients (MC and CC).

From: Mixed T cell lineage chimerism in acute leukemia/MDS using pre-emptive donor lymphocyte infusion strategy—Is it prognostic?—a single-center retrospective study

N = 217 patients

OS

  

NRM

  
 

HR (UV/MV)

CI (UV/MV)

P (UV/MV)

HR (UV/MV)

CI (UV/MV)

P (UV/MV)

Conditioning regimen (ref RIC)

1.2

0.8–1.83

0.21

1.7/1.9

0.9–3.1/1.07–3.5

0.07/0.06

Disease risk (DRI, ref low risk)

1.3

0.8–1.9

0.24

1.2

0.6–2.3

0.60

Age (ref < 52)

1.89/1.7

1.3–2.9/1.1–2.6

0.001/0.013

2.4 /2.7

1.3–5.2/1.3–5.7

0.03/0.04

Matching (ref 9/10)

0.60/0.65

0.4–0.8/0.43–0.9

0.02/0.019

0.65

0.3–1.2

0.20

MC vs CC (ref MC)

1.53/1.5

1.0–2.2/1.05–2.2

0.04/0.02

1.9/1.9

1.3–3.5/1.0–3.2

0.05/0.02

  1. OS overall survival, DFS disease-free survival, NRM non-relapse mortality, MA myeloablative regimen, RIC reduced-intensity conditioning, MC mixed chimerism, CC complete chimerism, pDLI pre-emptive donor lymphocyte infusion, NA not applicable.
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