Fig. 1: Biologic characteristics and survival outcomes of leukemias harboring RARA-variants. | Blood Cancer Journal

Fig. 1: Biologic characteristics and survival outcomes of leukemias harboring RARA-variants.

From: Characteristics and outcome of acute myeloid leukemia with uncommon retinoic acid receptor-alpha (RARA) fusion variants

Fig. 1

A Morphologic features of ZBTB16-RARA variant and flow cytometry characteristics of AML with RARA variants and PML-RARA-positive APL. The majority of blasts have hypergranular cytoplasm; in a minority of cases, Auer rods were present (UPN10 and UPN18). The majority of blasts harbored a regular round or oval nucleus that was more suggestive of FAB type M2; however, a minority of blasts in UPN 11 and UPN 18 showed irregular and indented nuclei. B Survival outcome of patients with RARA variant translocations.

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