Table 1 Definitions of plasma cell neoplasms.
From: Extramedullary disease in multiple myeloma: a systematic literature review
Plasma cell neoplasm | Definition |
|---|---|
Extramedullary disease | An aggressive form of multiple myeloma characterized by the presence of soft-tissue plasmacytomas that result from hematogenous spread |
Paraskeletal plasmacytoma | A form of multiple myeloma characterized by the presence of soft-tissue plasmacytomas that occur due to direct growth from skeletal tumors following cortical bone disruption |
Solitary plasmacytoma | A single mass of clonal plasma cells (bone or extramedullary) with no or minimal BM plasmacytosis and with no other symptoms than those derived from the primary lesion |
Plasma cell leukemia | A rare and aggressive variant of myeloma characterized by the presence of circulating plasma cells; diagnosis is based upon the percentage (≥20%) and absolute number (≥2 × 109/L) of plasma cells in peripheral blood |
