Table 3 Multivariate analysis for overall survival.

From: Evaluating complete remission with partial hematologic recovery (CRh) as a response criterion in myelodysplastic syndromes (MDS)

Variable

 

p value

Hazard ratio

95% Hazard ratio confidence limits

Allogeneic transplanta

 

<0.0001

0.44

0.304

0.636

Age

 

0.0236

1.018

1.002

1.034

WHO subgroup

MDS with Del5q

1.0

   

MDS NOS

0.3825

1.999

0.422

9.468

MDS-EB1

0.3056

2.12

0.504

8.921

MDS-EB2

0.3455

2.001

0.474

8.457

MDS-MLD

0.4139

1.819

0.433

7.637

MDS-SLD

0.3733

2.022

0.429

9.522

IPSS-R

Very low risk

1.0

   

Low risk

0.787

1.087

0.595

1.986

Intermediate risk

0.9906

1.004

0.546

1.844

High risk

0.1055

1.674

0.897

3.124

Very high risk

<0.0001

3.611

1.971

6.613

Treatment

Azacitidine

0.1592

1.259

0.914

1.736

Best overall response

CR

 

1.0

  

CRh

0.3156

1.281

0.79

2.077

SD

0.033

1.605

1.039

2.48

mCR

0.0686

1.712

0.96

3.052

PR

0.9494

1.067

0.142

8.016

PD

<0.0001

3.038

1.91

4.831

  1. aAllogeneic transplant status was considered as a time-varying covariate.
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