Table 2 Difference in therapeutic approaches between high- and low-volume centers.

From: Institutional factors associated with early mortality of newly diagnosed acute promyelocytic leukemia

  

High-volume center (n = 462)

Low-volume center (n = 676)

P value

Initiation of all-trans retinoic acid

≤1 day after admission

384 (83%)

514 (76%)

0.004

>1 day after admission

78 (17%)

162 (24%)

Initiation of conventional chemotherapy

≤7 days after admission

253 (55)

274 (41)

<0.001

>7 days after admission

108 (23)

221 (33)

Not performed

101 (22)

181 (27)