Table 2 Cox proportional hazard model for Time to Next Treatment (TTNT) and Overall Survival (OS) by Minimal Residual Disease (MRD) levels at day 100 Post-Autologous Stem Cell Transplant (ASCT).

From: Integrated analysis of next generation sequencing minimal residual disease (MRD) and PET scan in transplant eligible myeloma patients

 

Time to Next Treatment (TTNT)

Overall Survival (OS)

MRD level at Day 100 post-ASCT

Adjusted Hazard Ratio

95% Confidence Interval

P-value

Adjusted Hazard Ratio

95% Confidence Interval

P-value

[10−5–104] vs >10−4

0.699

0.312–1.563

0.38

0.938

0.240–3.668

0.93

[10−6–105] vs >10−4

0.692

0.319–1.502

0.35

1.237

0.355–4.316

0.74

< 10−6 vs > 10−4

0.289

0.1100.758

0.01*

0.619

0.160–2.401

0.49

  1. Bold values identify statistical significance (p < 0.05)