Fig. 3: CAR-T cell expansion and persistence.
From: Allogenic and autologous anti-CD7 CAR-T cell therapies in relapsed or refractory T-cell malignancies
A Kinetics of CAR vector transgene copies per microgram of genomic DNA of peripheral blood mononuclear cells in individual patients measured by ddPCR. The dotted line indicated the threshold determined by quantitation of normal samples. B Kinetics of CD7- CAR-T cells in peripheral blood detected by FCM. C Correlation of the peak CAR copies in the peripheral blood with sources and efficacy. D The percentages of CD7+ T cells were determined by FCM. Due to the lack of specimens, the condition of patients 1 and 2 could not be detected.
