Fig. 3: Mutational spectrum stratified by age group.

A Forest plot indicating the OR and 95% CIs for the association between recurrently mutated genes and age > 76 years, and a pyramid plot displaying the proportion of patients and absolute numbers with a mutation in the recurrently mutated genes per age group. B Boxplot with the distribution of the highest VAF per individual stratified by age group. C Violin plot showing the distribution of the number of mutations per individual stratified by age group.