Fig. 4: Mutational spectrum stratified by sex.

A Forest plot indicating the OR and 95% CIs for the association between recurrently mutated genes and male sex, and a pyramid plot displaying the proportion of patients and absolute numbers with a mutation in the recurrently mutated genes for male and female patients. B Boxplot with the distribution of the highest VAF per individual in female and male patients. C Violin plot showing the distribution of the number of mutations per individual in female and male patients.