Table 3 Multivariable Cox proportional-hazards regression for overall survival.
Variable | HR | 95%CI | p-value | |
|---|---|---|---|---|
Treatment | R-CHOP | 1 | ||
R2CHOP | 0.51 | (0.26–1.00) | 0.049 | |
Sex | Male | 1 | ||
Female | 0.55 | (0.29–1.06) | 0.074 | |
Age at incidence (years) | 1.03 | (1.00–1.06) | 0.025 | |
Ann Arbor stage | 2 | 1 | ||
3 | 0.50 | (0.15–1.61) | 0.24 | |
4 | 0.88 | (0.29–2.66) | 0.82 | |
Extra-nodal localizations | None | 1 | ||
1 | 0.55 | (0.23–1.32) | 0.18 | |
2 or more | 0.63 | (0.27–1.47) | 0.28 | |
LDH | Within normal range | 1 | ||
Elevated | 3.96 | (1.42–11.06) | 0.009 | |
WHO PS (grouped) | 0 | 1 | ||
1 | 1.41 | (0.68–2.93) | 0.36 | |
2 or 3 | 2.17 | (0.98–4.79) | 0.056 | |
Rearrangement | Single hit | 1 | ||
Double/triple hit | 0.98 | (0.49–1.94) | 0.95 | |
Missing BCL2/BCL6 | 0.49 | (0.16–1.53) | 0.22 |
