Fig. 2: Characteristics of predicted biallelic samples compared to known biallelic samples. | Blood Cancer Journal

Fig. 2: Characteristics of predicted biallelic samples compared to known biallelic samples.

From: Identifying novel mechanisms of biallelic TP53 loss refines poor outcome for patients with multiple myeloma

Fig. 2

A Gene expression heatmap of 16 signature genes across NDMM samples in the validation and discovery sets. B Dysregulated pathways enriched by the 16 signature genes; Kaplan‒Meier survival curves for ‘known’ biallelic, ‘predicted’ biallelic, ‘predicted’ mono-allelic and ‘known’ wild-type TP53 groups for progression-free survival (C) and overall survival (D). TPR true positive rate, FPR false positive rate, AUROC area under ROC.

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