Table 1 Number of samples and their TP53 abnormalities.
State | Set | Group | TP53 abnormalities (N =) | |||
|---|---|---|---|---|---|---|
Mutation | CNV | LOH | Total | |||
NDMM (N = 634) | Training | Known biallelic | 16 | 15 | 1 | 16 |
Known WT | Â | Â | Â | 377 | ||
Validation | Known biallelic | 7 | 7 | 0 | 7 | |
 predicted as biallelic |  |  |  | 7 | ||
 predicted not |  |  |  | 0 | ||
Known WT | Â | Â | Â | 165 | ||
 predicted as biallelic |  |  |  | 48 | ||
 predicted not |  |  |  | 117 | ||
Discovery | Known mono-allelic | 8 | 42 | 12 | 62 | |
 predicted as biallelic | 4 | 18 | 4 | 26 | ||
 predicted not | 4 | 24 | 8 | 36 | ||
RRMM (N = 66) | Validation | Known biallelic | 4 | 4 | 0 | 4 |
 predicted as biallelic |  |  |  | 4 | ||
 predicted not |  |  |  | 0 | ||
Known WT | Â | Â | Â | 47 | ||
 predicted as biallelic |  |  |  | 25 | ||
 predicted not |  |  |  | 22 | ||
Discovery | Known mono-allelic | 4 | 11 | 0 | 15 | |
 predicted as biallelic | 2 | 5 | 0 | 7 | ||
 predicted not | 2 | 6 | 0 | 8 | ||
