Fig. 1: Genetic profile and clinical outcome of NDMM patients with t(14;16). | Blood Cancer Journal

Fig. 1: Genetic profile and clinical outcome of NDMM patients with t(14;16).

From: Prognostic impact of translocation t(14;16) in multiple myeloma according to the presence of additional genetic lesions

Fig. 1

A Frequencies of prognostic abnormalities according to t(14;16) status. The black bars correspond to 4972 newly diagnosed patients without t(14;16), the red bars to 169 newly diagnosed patients with t(14;16). Categorical data are presented as percentages and compared using a chi-square test. ***P < 0.0001, *P = 0.013. B Kaplan–Meier progression-free and overall survival of patients with NDMM according to cytogenetics. The red curve corresponds to all patients with t(14;16), the blue dotted curve to patients with t(14;16) but without deletion 17p, TP53 mutation, gain/amp 1q, deletion 1p32, the black curve to patients without t(14;16). P values are determined by the log-rank test comparison.

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