Table 1 Baseline characteristics.
From: Muscle and fat composition in patients with newly diagnosed multiple myeloma
Median (IQR) | N (%) | |
|---|---|---|
Age (years) | 65 (59–72) | |
Age > 65 years | 176 (52) | |
Age > 70 years | 108 (32) | |
Sex (Male) | 226 (66) | |
BMI (kg/m2) | 28.1 (24.6–31.7) | |
Underweight/Normal/Overweight/Obese (N = 338) | 2 (1)/90 (27)/126 (37)/120 (36) | |
ISS III (vs. I/II) (N = 312) | 86 (28) | |
R-ISS III (vs. I/II) (N = 280) | 36 (13) | |
Laboratory data: | ||
Hb < 10 g/dL (N = 306) | 78 (25) | |
Platelets < 150 × 109/L (N = 276) | 47 (17) | |
Calcium > 11 mg/dL (N = 300) | 16 (5) | |
Creatinine > 2 mg/dL (N = 293) | 25 (9) | |
High LDH IU/La (N = 287) | 37 (13) | |
BMPCs (%) (N = 310) | 40 (20–69) | |
Heavy chain isotype (N = 293) | ||
IgG | 170 (58) | |
IgA | 70 (24) | |
IgM | 2 (1) | |
IgD | 3 (1) | |
None | 48 (16) | |
Light chain isotype (K/L) (N = 289) | 200 (69)/89 (31) | |
ASCT | 184 (54) | |
First-line induction (N = 323) | ||
PI | 109 (34) | |
IMiD | 85 (26) | |
PI+IMiD | 123 (38) | |
Other | 6 (2) | |
FISH abnormalities | ||
HR IgH translocation (N = 331) | 50 (15) | |
Trisomy (any) (N = 329) | 182 (55) | |
1q gain (N = 304) | 86 (28) | |
MYC abnormality (N = 301) | 27 (9) | |
Monosomy 13 (N = 335) | 137 (41) | |
Del17p/monosomy 17 (N = 332) | 48 (14) | |
