Table 2 Multivariable cause-specific Cox regression of baseline characteristics for time to first severe infections.
From: Comparison of infectious complications with BCMA-directed therapies in multiple myeloma
Characteristic | N | Event | HR | 95% CI | P value |
|---|---|---|---|---|---|
Cohort | |||||
BsAb | 53 | 21 | - | - | |
CAR-T | 92 | 24 | 0.60 | 0.31, 1.17 | 0.14 |
Age | 145 | 45 | 0.99 | 0.96, 1.02 | 0.5 |
Refractory Status | |||||
Neither | 25 | 7 | - | - | |
Triple | 59 | 18 | 0.91 | 0.36, 2.32 | 0.8 |
Penta- | 61 | 20 | 1.29 | 0.50, 3.29 | 0.6 |
Prior BCMA therapy | 145 | 45 | 0.65 | 0.28, 1.48 | 0.3 |
Neutropenia ≤ 500/mm | 145 | 45 | 1.78 | 0.37, 8.46 | 0.5 |
Lymphopenia ≤ 500/mm | 145 | 45 | 1.80 | 0.92, 3.53 | 0.086 |
Hypogammaglobulinemia | 145 | 45 | 1.11 | 0.59, 2.07 | 0.8 |