Table 2 Multivariable cause-specific Cox regression of baseline characteristics for time to first severe infections.

From: Comparison of infectious complications with BCMA-directed therapies in multiple myeloma

Characteristic

N

Event

HR

95% CI

P value

Cohort

BsAb

53

21

-

-

 

CAR-T

92

24

0.60

0.31, 1.17

0.14

Age

145

45

0.99

0.96, 1.02

0.5

Refractory Status

Neither

25

7

-

-

 

Triple

59

18

0.91

0.36, 2.32

0.8

Penta-

61

20

1.29

0.50, 3.29

0.6

Prior BCMA therapy

145

45

0.65

0.28, 1.48

0.3

Neutropenia ≤ 500/mm

145

45

1.78

0.37, 8.46

0.5

Lymphopenia ≤ 500/mm

145

45

1.80

0.92, 3.53

0.086

Hypogammaglobulinemia

145

45

1.11

0.59, 2.07

0.8

  1. BsAb bispecific antibodies, CAR-T chimeric antigen receptor T-cell therapy, BCMA B-cell maturation antigen, HR hazard ratio, CI confidence interval.