Table 2 Cell populations analyzed in NLPHL and THRLBCL.
Cell types (Z-scores) | Phenotype | NLPHL | THRLBCL | ||
|---|---|---|---|---|---|
Group 1 | Group 2 | Group 3 | |||
B-cell subsets | |||||
Tumor Ba | CD20/BCL6 | −0.47 | −0.35 | 0.36 | 1.10 |
TME B | CD20/IgD | 0.77 | 0.28 | −0.38 | −1.61 |
T-cell subsets | |||||
Helper T | CD3/CD4 | 0.50 | 0.15 | −1.06 | −0.40 |
Activated Helper T | CD3/CD4/LAG3/CD69 | −0.14 | −0.00 | 1.01 | −0.48 |
Follicular Helper T (TFH) | CD3/CD4/PD1/BCL6 | 0.16 | 0.32 | −0.05 | −0.68 |
Activated TFH (aTFH) | CD3/CD4/PD1/BCL6/LAG3/CD69 | −0.55 | −0.37 | 0.52 | 1.18 |
Cytotoxic T-cells | CD3/CD8 | −0.05 | −0.04 | −0.21 | 0.29 |
Activated cytotoxic T | CD3/CD8/LAG3/CD69 | −0.39 | 0.19 | 0.03 | 0.50 |
Regulatory T-cells (T-reg) | CD3/CD4/FOXP3 | −0.31 | 0.14 | 0.12 | 0.34 |
CD4/CD8 double-positive T (DPT) | CD3/CD4/CD8 | 0.17 | 0.24 | −0.09 | −0.59 |
Macrophage/Monocyte subsets | |||||
Macrophages | CD68 | −0.21 | −0.29 | −0.03 | 1.02 |
Monocytes | CD68/MPO/CD14 | −0.54 | 0.12 | 0.18 | 0.79 |
