Fig. 2: Consensus clustering is associated with BTK expression in all other 4 cohorts. | Blood Cancer Journal

Fig. 2: Consensus clustering is associated with BTK expression in all other 4 cohorts.

From: Transcriptomic clustering of chronic lymphocytic leukemia: molecular subtypes based on Bruton’s tyrosine kinase expression levels

Fig. 2

Normalization of expression data is performed using RMA and DESeq2 algorithms on Affymetrix microarray (Set2) and RNA sequencing (Set3, Set4, and Set5) datasets respectively. BTK subtypes are generated using the same consensus clustering methodology in other four cohorts. BTK subtypes in each of these cohorts are significantly associated (p < 0.05) with BTK mRNA Expression (A-Set2, B-Set3, C-Set4 and D-Set5).

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