Fig. 8: Higher levels of cleaved caspases, cyclins D1/D3 in BTK-Low, while higher replication related proteins in BTK-high subtype.

Significant differentially expressing proteins in the apoptosis pathway— caspase 7 (A) and caspase 8 (B), G1 cell cycle (Cyclin D1 (C) and Cyclin D3 (D)), and replication protein total RPA32 (E) and phospho-RPA32 (F) are shown.