Fig. 2: Transcriptomic analysis of VTX-sensitive and resistant samples. | Blood Cancer Journal

Fig. 2: Transcriptomic analysis of VTX-sensitive and resistant samples.

From: Exploring BCL2 regulation and upstream signaling transduction in venetoclax resistance in multiple myeloma: potential avenues for therapeutic intervention

Fig. 2

A, B Visualization of KEGG-based enrichment analysis of differentially expressed genes between two (OCIMy7 and SKMM2) venetoclax-resistant and sensitive cell lines. C Comprehensive pathways analysis contrasting all collected venetoclax-resistant cell lines (primary patient samples and human cell lines) with sensitive samples, highlighting differentially regulated pathways; orange color shows pathway activation in resistant samples, and blue shows pathway suppression.

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