Table 1 Baseline characteristics of the study population.

From: Characteristics and predictors of central nervous system relapse in newly diagnosed acute promyelocytic leukemia in the era of arsenic: a 13-year monocenter cohort study

Characteristics

Total (n = 910)

N (%)/median [range]

Relapse (n = 80)

N (%)/median [range]

Age, years

44 [14–88]

47 [15–77]

Gender

 M

484 (53.2)

48 (60.0)

 F

426 (46.8)

32 (40.0)

WBC count, ×109/L

2 [0.2–160]

2.3 [0.4–75]

HGB, g/L

94 [19–169]

96 [34–154]

PLT count, ×109/L

27 [1–356]

26 [4–225]

Sanz risk

 Low

259 (28.4)

26 (32.5)

 Intermediate

382 (42.0)

33 (41.2)

 High

199 (21.9)

21 (26.3)

 Missing data

70 (7.7)

0 (0.0)

Fibrinogen, mg/dL

134 [20–1520]

125 [49–580]

D-dimer, ug/mL

11.6 [0.1–133]

8.2 [0.2–100]

FLT3-ITD mutation

185 (20.3)

22 (27.5)

Period

 2011–2015

284 (31.2)

32 (40.0)

 2016–2023

626 (68.8)

48 (60.0)

  1. WBC white blood cell, HGB hemoglobin, PLT platelet, FLT3-ITD Internal tandem duplication of FMS-like tyrosine kinase-3.
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