Table 3 Inter-relationship of imaging response, MRD and serological response assessments.

From: Whole body MRI by MY-RADS for imaging response assessment in multiple myeloma

A

 

Bone marrow MRD

Total

p value1

Negative

Positive

Imaging response

   

0.3

  RAC1

24 (44%)

13 (24%)

37 (67%)

 

  RAC2+

9 (16%)

9 (16%)

18 (33%)

 

Total

33 (60%)

22 (40%)

55 (100%)

 

B

 

IMWG response

Total

p value1

sCR/CR

<CR

Imaging response

   

0.5

  RAC1

25 (36%)

22 (32%)

47 (68%)

 

  RAC2+

10 (14%)

12 (17%)

22 (32%)

 

Total

35 (51%)

34 (49%)

69 (100%)

 

C

Characteristic

HR1

95% CI1

p value

Imaging response

 RAC1

—

—

 

 RAC2+

2.08

1.01, 4.31

0.048

IMWG response

 CR

—

—

 

 <CR

2.00

0.98, 4.08

0.057

2 + HRCA

1.43

0.89, 2.28

0.14

  1. 1Pearson’s Chi-squared test.
  2. HR Hazard ratio, CI confidence interval.
  3. Cross tables for A bone marrow MRD and imaging response as per MY-RADS (n = 55 patients with both variables) B IMWG serological and imaging response (n = 70). Multivariable Cox-regression analysis C of imaging response assessment in a model including serological response and HRCA (n = 65).
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