Table 1 Characteristics of transplanted (N = 132) and non-transplanted (N = 368) childhood cancer survivors, matched by sex, age at diagnosis, diagnosis, and year of diagnosis (1:3 ratio).

	Transplanted CCS (n = 132)	Non-transplanted CCS (n = 368)
	n (%)	n (%)
Sociodemographic and lifestyle characteristics
Sex, male	69 (52)	195 (53)
Age at questionnaire, median years (IQR)	18.4 (13.8–22.9)	18.5 (13.6–23.8)
Smoking status^a
Active smoking	7 (5)	27 (7)
Passive smoking	63 (48)	163 (44)
Former active smoking	9 (6)	20 (6)
Never smoking	54 (41)	158 (43)
Clinical characteristics
Age at diagnosis, median years (IQR)	6.5 (2.9–11.6)	6.4 (2.7–11.4)
Age at transplantation, median years (IQR)	8.8 (4.8–13.6)	NA
Follow-up time^b, median years (IQR)	9.8 (7.2–15.9)	10.1 (7.9–15.1)
Era of diagnosis
1976–1995	40 (30)	120 (33)
1996–2005	60 (45)	156 (42)
2006–2010	32 (25)	92 (25)
Childhood cancer diagnosis according to ICCC-3
I: Leukemia	72 (55)	214 (58)
II: Lymphoma	20 (15)	60 (16)
IV: Neuroblastoma	19 (14)	44 (12)
Other^c	21 (16)	50 (14)

CCS childhood cancer survivors, ICCC-3 International Classification of Childhood Cancer, 3rd edition, IQR interquartile range.
^a“Active” and “former active smoking” assessed in adolescents and adults; “passive smoking” in children corresponds to having parents who currently smoke or formerly smoked, “never smoking” in children corresponds to having both parents who never smoked.
^bTime from first diagnosis until date of answering the questionnaire.
^cOther tumors in transplanted survivors include: tumors of the central nervous system (n = 6), retinoblastoma (n = 1), malignant bone tumors (n = 7), soft tissue sarcomas (n = 4), malignant germ cell tumors (n = 3) Other tumors in non-transplanted survivors include: tumors of the central nervous system (n = 12), retinoblastoma (n = 1), malignant bone tumors (n = 9), soft tissue sarcomas (n = 4), malignant germ cell tumors (n = 3).

Search