Table 1 Patient characteristics.
From: Early bilirubinemia after allogeneic stem cell transplantation—an endothelial complication
Cohort | Training, n = 898, | Validation, n = 399, | p |
|---|---|---|---|
Transplantation period | 05/2001–12/2013 | 01/2013–12/2015 | |
n (%) | n (%) | ||
EB, no SOS/VOD | 88 (10) | 62 (16) | 0.075 |
EB and SOS/VOD | 28 (3) | 39 (10) | |
SOS/VOD | 43 (5) | 44 (11) | |
SOS/VOD no EB (Bili < 3.5) | 15 (2) | 5 (1) | |
Age (median, range) | 54 (17–76) | 55 (18–75) | 0.081 |
Statins + UDA (SEP) | 501 (56) | 0 (0) | <0.001 |
disease stage high [51] | 343 (38) | 227 (57) | <0.001 |
AML | 283 (32) | 204 (51) | <0.001 |
ALL | 39 (4) | 30 (8) | |
MDS | 111 (12) | 33 (8) | |
MPN | 66 (7) | 43 (11) | |
Lymphoma | 268 (30) | 35 (9) | |
MM | 130 (14) | 37 (9) | |
Others | 1 (0) | 17 (4) | |
related donor | 268 (30) | 238 (60) | <0.001 |
Mismatch <10/10 | 204 (23) | 79 (20) | 0.245 |
ATG | 576 (64) | 361 (90) | <0.001 |