Table 1 Baseline Characteristics of Participants.

From: Abatacept for the prevention of graft versus host disease in pediatric patients receiving 7/8 HLA-mismatched unrelated transplant for hematologic malignancies: a real-world analysis

Baseline Characteristics 

7/8 ABA

8/8 control

p value

 

(N = 27)

(N = 65)

 

Age at transplant, years

  

0.65

  Median (range)

12 (1–22)

11 (<1–24)

 

Age at transplant, grouped, no. (%)

  

0.16

  0–9 years

13 (48)

26 (40)

 

  10–19 years

11 (41)

37 (57)

 

  20–24 years

3 (11)

2 (3)

 

Sex, no. (%)

  

0.07

  Male

18 (67)

29 (45)

 

  Female

9 (33)

36 (55)

 

Race, no. (%)

  

0.01

  White

13 (48)

47 (72)

 

  Black/African American

12 (44)

10 (15)

 

  Asian

2 (7)

3 (5)

 

  Unknown

0

5 (8)

 

Ethnicity, no. (%)

  

0.68

  Hispanic or Latino

7 (26)

11 (17)

 

  Not Hispanic or Latino

19 (70)

51 (78)

 

  Unknown

1 (4)

3 (5)

 

Primary disease for transplant, no. (%)

  

0.05

  AML

13 (48)

20 (31)

 

  ALL

7 (26)

34 (52)

 

  CML

3 (11)

1 (2)

 

  MDS

3 (11)

6 (9)

 

  Other

1 (4)

4 (6)

 

Disease stage, no. (%)

  

0.0002

  Early

19 (70)

18 (28)

 

  Intermediate

6 (22)

43 (66)

 

  Advanced

2 (7)

3 (5)

 

  Not categorized

0

1 (2)

 

Conditioning regimen, no. (%)

  

0.11

  Busulfan/Fludarabine

9 (33)

11 (17)

 

  Busulfan/Cyclophosphamide

7 (26)

13 (20)

 

  Total Body Irradiation/Cyclophosphamide

7 (26)

35 (54)

 

  Fludarabine/Melphalan

2 (7)

3 (5)

 

  Clofarabine/Busulfan/Fludarabine

2 (7)

3 (5)

 

Conditioning intensity, no. (%)

  

0.63

  Myeloablative

25 (93)

62 (95)

 

  Reduced Intensity

2 (7)

3 (5)

 

Graft type, no. (%)

  

0.63

  Bone marrow

25 (93)

62 (95)

 

  Peripheral blood

2 (7)

3 (5)

 

Median follow-up of survivors, months

  

0.87

  Median (range)

24 (6–66)

25 (7–69)

 
  1. AML acute myelogenous leukemia, ALL acute lymphatic leukemia, CML chronic myelogenous leukemia, MDS myelodysplastic syndrome.