Table 23

From: The 49th Annual Meeting of the European Society for Blood and Marrow Transplantation: Physicians - Oral Sessions (O009-O172)

 

IA before HCT

No

(N = 1432)

IA before HCT

Yes

(N = 95)

Total

(N = 1527)

Age at HCT Median (min – max)

40.9 (0.4–75.8)

36.6 (1.2–68.0)

40.9 (0.4–75.8)

Interval from IA to HCT (months)

 

6.6 (2.2–165.3)

 

Underlying malignancy

   

 ALL

460 (32.1)

33 (34.7)

493 (32.3)

 AML

972 (67.9)

62 (65.3)

1034 (67.7)

Acute leukemia status before HCT

   

 Other

1099 (76.7)

79 (83.2)

1178 (77.1)

 CR

310 (21.6)

15 (15.8)

325 (21.3)

Donor type

   

 HLA-identical sibling

363 (25.3)

38 (40.0)

401 (26.3)

 Haploidentical

233 (16.3)

17 (17.9)

250 (16.4)

 Unrelated donor

836 (58.4)

40 (42.1)

876 (57.4)

Stem cell source

   

 Bone marrow

373 (26.0)

20 (21.1)

393 (25.7)

 Peripheral Blood

1014 (70.8)

72 (75.8)

1086 (71.1)

 Cord Blood

45 (3.1)

3 (3.2)

48 (3.1)

Conditioning regimen

   

 Myeloablative

1081 (75.5)

80 (84.2)

1161 (76.0)

 Reduced

348 (24.3)

14 (14.7)

362 (23.7)

Total body irradiation

   

 No

999 (69.8)

62 (65.3)

1061 (69.5)

 Yes

430 (30.0)

30 (31.6)

460 (30.1)

In-vivo T-cell depletion

   

 No

714 (49.9)

51 (53.7)

765 (50.1)

 Yes

716 (50.0)

43 (45.3)

759 (49.7)