Table 54 Table displays the mobilization outcomes for each diagnosis by mobilisation regimen.
|  | G-CSF | Cyclo-G | Other chemotherapy + G-CSF | G-CSF vs Cyclo-G (p value) | G-CSF vs other-G (p value) | Cyclo-G vs other-G (p value) |
|---|---|---|---|---|---|---|
Multiple Myeloma | Â | Â | Â | Â | Â | Â |
Number of patients | 438 | 319 | 45 | Â | Â | Â |
Pre-CD34+ count (x106/kg) Median (Q1-Q3) | 29 (18–54) | 40 (21–75) | 23 (15–53) | <0.0001 | ns | <0.0001 |
CD34+ yield per procedure (x106/kg) Median (Q1-Q3) | 2.01 (1.16–3.30) | 3.65 (1.87–6.23) | 2.01 (1.20–5.04) | <0.0001 | ns | <0.0001 |
CD34+ yield per patient (x106/kg) Median (Q1-Q3) | 4.75 (3.47–6.3) | 7.44 (5.44–9.61) | 5.75 (3.72–7.84) | <0.0001 | ns | <0.0001 |
Plerixafor use N (%) | 41 (9.3%) | 11 (3.4%) | 15 (33%) | <0.001 | <0.00001 | <0.00001 |
NHL | Â | Â | Â | Â | Â | Â |
Number of patients | 142 | 47 | 189 | Â | Â | Â |
Pre-CD34+ count (x106/kg) Median (Q1-Q3) | 23 (14–43) | 19 (11–30) | 28 (15–72) | NS | NS | 0.0055 |
CD34+ yield per procedure (x106/kg) Median (Q1-Q3) | 1.53 (0.89–3.19) | 1.19 (0.80-3.04) | 2.93 (1.30-5.87) | NS | <0.00001 | <0.00001 |
CD34+ yield per patient (x106/kg) Median (Q1-Q3) | 3.70 (2.65–5.89) | 3.69 (2.60–6.50) | 5.98 (3.85–8.93) | NS | <0.00001 | <0.00001 |
Plerixafor use N (%) | 37 (26%) | 4 (9%) | 37 (20%) | 0.011 | NS | NS |
Hodgkin’s Lymphoma |  |  |  |  |  |  |
Number of patients | 44 | 16 | 30 | Â | Â | Â |
Pre-CD34+ count (x106/kg) Median (Q1-Q3) | 33 (16–63) | 35 (18–64) | 37 (16–63) | NS | NS | NS |
CD34+ yield per procedure (x106/kg) Median (Q1-Q3) | 1.94 (0.97–4.78) | 3.02 (1.61–6.85) | 2.10 0/96–4.38) | NS | NS | NS |
CD34 yield per patient Median (Q1-Q3) | 4.53 (2.99–7.44) | 5.52 (3.02–5.52) | 4.32 (2.99–8.05) | NS | NS | NS |
Plerixafor use N (%) | 6 (14%) | 2 (9 %) | 8 (27%) | NS | NS | NS |