Table 4 Changes in laboratory parameters in surviving patients (n = 7).

From: Eculizumab treatment in paediatric patients diagnosed with aHUS after haematopoietic stem cell transplantation: a HSCT-TMA case series from Japanese aHUS post-marketing surveillance

Laboratory parameter

At initiation of ECZ

At discontinuation of ECZ

Pa

Last observation

Pa

PLT count, ×109/L

32

(14–43)

58

(38–164)

0.073

186

(106–258)

0.011

LDH, U/L

652

(509-808)

283

(224–322)

<0.01

232

(198–261)

<0.01

sCr, mg/dL

0.49

(0.26-0.89)

0.37

(0.28–0.61)

0.79

0.39

(0.36–0.65)

0.79

  1. Values are median (IQR).
  2. ECZ eculizumab, eGFR estimated glomerular filtration rate, LDH lactate dehydrogenase, PLT platelet, sCr serum creatinine.
  3. aP-values versus at the initiation of eculizumab.
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