Fig. 4: Engrafted mice display reduced IFN-g producing CD4+ and CD8+ T cells and NK cells. | Bone Marrow Transplantation

Fig. 4: Engrafted mice display reduced IFN-g producing CD4+ and CD8+ T cells and NK cells.

From: Low dose post-transplant cyclophosphamide and sirolimus induce mixed chimerism with CTLA4-Ig or lymphocyte depletion in an MHC-mismatched murine allotransplantation model

Fig. 4

Splenocyte analysis at 4 weeks PT of host-derived H2- kb+ CD4+ IFN- γ+ T cells a, H2- kb+ CD8+ IFN- γ+ T cells b, and H2- kb+ CD4+ IFN- γ+ NK cells c. Data shown from a representative experiment involving n = 4 mice (Mean ± SEM). *P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001 (unpaired two-tailed Student’s t-test).

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