Table 2 Transplant outcomes.
Patient | Antifungal | Therapy changed? | Duration of Neutropenia (days) | GVHD | Granulocytes | Radiology Improved? | Days to death | Outcome |
|---|---|---|---|---|---|---|---|---|
1 | PO VRC | No change | 17 | No | No | N/A | N/A | Success |
2 | Liquid POSA, IV VRC, echino | No change | 10 | No | Yes | Yes | N/A | Success |
3 | Liquid POSA, PO then IV VRC | Added AMB and echino | 44 | No | No | No | 663 | Death (Evan’s syndrome, infection recurrence) |
4 | IV VRC, echino, TRB | No change | 8 | N/A | Yes | Yes | N/A | Success |
5 | IV VRC, echino, AMB | No change | 8 | Yes | Yes | N/A | 91 | Death (alveolar hemorrhage) |
6 | Liquid POSA, Po then IV VRC (1 dose IV only) | Added AMB and echino | 14 | Yes | No | Nob | N/A | Success |
7 | PO then IV VRC, echino | No change | 17 | No | Yes | Yes | N/A | Success |
8 | ITC and VRC IV | Added AMB and echino | 19 | Yes | No | Yes | 296 | Death (status epilepticus, CNS Aspergillosis) |
9 | Liquid POSA | No change | 10 | No | No | Yes | N/A | Success |
10 | PO POSA, echino, AMB, TRB | No change | 4 | No | Yes | Yes | N/A | Success |
11 | PO then IV POSA, echino, TRB | Added AMB | 21 | Yes | Yes | Yes | N/A | Success |
12 | FLC | Added IV POSAA, AMB and echino | 16 | No | No | Yes | N/A | Success |
13 | IV POSA, echino, TRB | No change | 23 | Yes | Yes | Yes | N/A | Success |
14 | ITC | Added AMB and echino, changed to POSA liquid then PO then IV | 21 | Yes | No | N/A | 316 | Death (alveolar hemorrhage, liver GVHD) |
15 | PO VRC, echino | Changed to IV then liquid VRC | 12 | Yes | No | Yesc | N/A | Success |
16 | PO POSA, echino, TRB | No change | 14 | No | Noa | Yes | N/A | Success |
17 | Liquid POSA, ISA | Added TRB | 2 | No | No | Yes | N/A | Success |
18 | IV POSA, echino, AMB, TRB | No change | 18 | No | Yes | N/A | 44 | Death (autoimmune thrombocytopenia, intracranial hemorrhage) |
19 | IV then PO then IV ISA, echino, TRB | No change | 9 | N/A | Yes | Yes | 25 | Death (engraftment syndrome, TRALI) |
20 | IV AMB | Added IV POSA | 14 | N/A | Yes | N/A | 39 | Death (engraftment syndrome) |
21 | PO POSA | No change | 15 | No | No | Yes | N/A | Success |
22 | IV then PO ISA, PO then IV POSA, TRB | No change | 3 | No | No | Yes | N/A | Success |
23 | PO then IV POSA | Added AMB and echino | 23 | Yes | No | Yes | N/A | Success |
24 | PO POSA, ISA, echino, TRB | No change | 13 | No | No | Yes | N/A | Success |
25 | PO then IV POSA, echino, TRB | No change | 26 | No | No | Yes | N/A | Success |
26 | PO POSA, echino, TRB | Changed to liquid then IV POSA | 25 | No | No | Yes | 263 | Death (sepsis and liver aspergillosis) |
