Fig. 3
From: Bone loss from Wnt inhibition mitigated by concurrent alendronate therapy
Effects of ETC-159 and alendronate on static bone histomorphometry. a Brightfield images of trichrome stained femoral sections from the indicated groups. Static histomorphometry of sagittal sections measured. b Bone volume (BV)/tissue volume (TV) c trabecular number, d trabecular diameter, e trabecular separation. Mice per group was vehicle (n = 5), alendronate (n = 3), ETC-159 (n = 5), and ETC-159 and alendronate, (n = 6). The data represent the mean ± S.D. **P ≤ 0.01, ***P ≤ 0.001.
