Fig. 2
From: Osteoclast-derived apoptotic bodies couple bone resorption and formation in bone remodeling
Proteomic profiling of ABs from BMMs, pOCs, and mOCs. a Heat map visualization of hierarchical clustering showing the expression profile of 4 306 proteins identified in ABs. b Venn diagrams comparing the total proteomes of different types of ABs. c Subcellular localization analysis showing the intracellular distribution of all DEPs. The DEPs were localized mainly in the cytoplasm, nucleus, and mitochondria. d Volcano plots showing the DEPs in the three comparison groups. The red dots represent DUPs (FC > 2.0), and the blue dots represent DDPs (FC < 0.5)
