Fig. 6
MicroCT-based evaluation of loading of the proximal tibia of C57BL/6 mice and BALB/c mice. BV/TV bone volume ratio normalized by total volume, Tb.s trabecular separation, Tb.n trabecular number, and BMD bone mineral density. The single and double asterisks indicate P < 0.05 and P < 0.01, respectively. a, b Beneficial effects of tibia loading (1 N) on the proximal tibiae of C57BL/6 mice (N = 10 per group). c, d Detrimental effects of tibia loading (2 and 5 N) on the proximal tibiae of C57BL/6 mice (N = 10 per group). e, f Detrimental effects of tibia loading (5 N) on the proximal tibiae of BALB/c mice (N = 10 per group)
