Fig. 7
Histological analysis of the proximal tibiae and distal femurs of BALB/c mice in response to tibia loading (5 N). a, b Sagittal section of the tibia of the sham-control sample and tibia-loaded sample. The tibia-loaded samples presented more osteolytic lesions than those of the sham-control samples. c, d Quantification of bone area and tumor area in H&E-stained tibia sections. The area of the 5-N group is normalized to that of the sham-loading group. e Increase in the number of microcracks in cortical bone of the tibia-loaded samples
