Fig. 3
From: Endocrine role of bone in the regulation of energy metabolism
Exosomes and inflammatory factors are mainly secreted by BMSCs. After forming vesicles containing various active substances, exosomes are released into the extracellular matrix. The inflammatory factors released by BMSCs can be divided into proinflammatory factors and anti-inflammatory factors. Exosomes and inflammatory factors can regulate distant target organs, thus leading to an inflammatory response, obesity, insulin resistance, etc
