Fig. 1 | Bone Research

Fig. 1

From: Intervertebral disc degeneration is rescued by TGFβ/BMP signaling modulation in an ex vivo filamin B mouse model

Fig. 1

Flnb−/− IVD exhibits ectopic mineralization. a, b P21 IVD plastic sagittal sections with Von Kossa staining. a Flnb+/+ IVD exhibiting blue–violet fibrocartilage in AF IVD tissue (white arrows). b Flnb−/− IVD exhibits black–brown staining in the AF representing mineralization of the AF tissue (yellow arrows). AF also exhibits the characteristics of trabecular bone, an indication that it is undergoing full ossification. n = 3, Representative image of T7-T8 IVD in individual mice

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