Table 3 Mouse skeletal stem cells labeled by immunophenotypic markers
Surface markers | Location | Features | References |
|---|---|---|---|
PDGFRα+Sca1+ | Perivascular | Bone and adipose formation, hematopoiesis-supportive | |
CD45−Ter119−Tie2−AlphaV+Thy−6C3−CD105−CD200+ | Femoral growth plate (mSSCs can be isolated from ribs and sternum as well) | Bone, cartilage, and stroma formation (but not adipose tissue); hematopoiesis-supportive; fracture repair | |
CD45−CD31−Sca1+CD24+ | Perivascular | PDGFRα+; bone, cartilage, and adipocytes formation; hematopoiesis-supportive | |
CD45−Ter119−CD31−CD166−CD146−Sca1+ | Mainly on the endosteal surface of trabecular bone in epiphysis | Bone and stroma formation, hematopoiesis-supportive |
