Fig. 5 | Bone Research

Fig. 5

From: MicroRNA-146a-loaded magnesium silicate nanospheres promote bone regeneration in an inflammatory microenvironment

Fig. 5The alternative text for this image may have been generated using AI.

MSNs+miR-146a accelerated bone regeneration in a stimulated infected mouse mandibular defect model. a, b Micro-CT examinations of mouse mandible samples after 2 weeks (a) and 4 weeks (b) of healing following surgery with representative reconstructed volume and slice images and the mean BV/TV, BMD and Tb.Sp (n = 7–10). c Maximal force detected in the three-point bending test of trimmed mouse mandible samples (n = 8). *P < 0.05, **P < 0.01, ***P < 0.001. One-way ANOVA with Dunnett’s multiple comparisons to the blank group was used

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