Fig. 1 | Bone Research

Fig. 1

From: Multi-omics analysis of human tendon adhesion reveals that ACKR1-regulated macrophage migration is involved in regeneration

Fig. 1

Single-cell atlas of human normal peritendinous tissue and tendon adhesion tissue. a Overview of this study design. Normal peritendinous tissue and tendon adhesion tissue were collected from tendon injury patients and processed for 3′-end scRNA-seq using the 10× Genomics platform. b UMAP plots of 74 350 cells from total 12 patients with tendon injury. 10 081 cells from normal peritendinous tissue of three patients. 18 866 cells from tendon adhesion tissue of three 3 dpi (day post injury) patients. 14 953 cells from tendon adhesion tissue of three 10 dpi patients. 30 450 cells from tendon adhesion tissue of three 12 wpi (week post injury) patients. c Dot plot: showing cell clusters of human tendon adhesion tissue by known markers. The dot size indicates the gene expression percent in each cluster. The color indicates mean gene expression (Red, high). d Bar plots of the proportion of eight major cell types in human tendon adhesion tissue of each time point. e Bar plots of the proportion of eight major cell types in human tendon adhesion tissue of each patient

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