Fig. 1 | Bone Research

Fig. 1

From: Age- and sex-specific deterioration on bone and osteocyte lacuno-canalicular network in a mouse model of premature aging

Fig. 1

Musculoskeletal decline in PolgA mice with aging. a Schematic indicating the experimental plan (created with Biorender). Analysis of body weight changes (b), frailty index (FI) (c), forelimb grip strength (d) and average speed (e) over time in male and female PolgA mice and WT littermates. n = 7–13 mice/group. Significance was determined by two-way ANOVA with Tukey’s post hoc test (*P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.000 1)

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