Fig. 6 | Bone Research

Fig. 6

From: Chemotherapeutic drug-triggered AEP-cleaved G3BP1 orchestrates stress granules/nucleoli/mitochondria in osteosarcoma

Fig. 6The alternative text for this image may have been generated using AI.

High levels of AEP and G3BP1 truncations in OS tumor tissues and strong association with poor prognosis. a WB analysis of G3BP1 cleavage and AEP activation in OS tumor tissues. b Correlation analysis of G3BP1 and AEP expression from TARGET RNA-seq data (n = 89). c Kaplan‒Meier survival curves for patients with low and high expression of G3BP1 and AEP [n(Low) = 48; n(High) = 47]. d Comparative expression analysis of G3BP1 in normal tissues versus glioblastoma (GBM) tumor tissues from TCGA RNA-seq database. e Kaplan‒Meier survival curves for GBM patients with low and high expression of G3BP1 [n(Low) = 338; n(High) = 338]. Data are expressed as mean ± SD. *P < 0.05. log-rank (Mantel-Cox) test

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