Fig. 6

High levels of AEP and G3BP1 truncations in OS tumor tissues and strong association with poor prognosis. a WB analysis of G3BP1 cleavage and AEP activation in OS tumor tissues. b Correlation analysis of G3BP1 and AEP expression from TARGET RNA-seq data (n = 89). c Kaplan‒Meier survival curves for patients with low and high expression of G3BP1 and AEP [n(Low) = 48; n(High) = 47]. d Comparative expression analysis of G3BP1 in normal tissues versus glioblastoma (GBM) tumor tissues from TCGA RNA-seq database. e Kaplan‒Meier survival curves for GBM patients with low and high expression of G3BP1 [n(Low) = 338; n(High) = 338]. Data are expressed as mean ± SD. *P < 0.05. log-rank (Mantel-Cox) test