Fig. 7

Regulation of M2 macrophage polarization by metal nanoparticle (NP)-based biomaterials for bone infection treatment. a Flow cytometry analysis showing enhanced M2 macrophage polarization induced by the AH-Sr-AgNPs delivery system in vitro. Reproduced with permission from ref. 300 Copyright 2019, Wiley-VCH. b Biomimetic anti-inflammatory nanocapsules (BANC) based on gold nanocages (AuNCs) promote bone tissue repair by inducing M2 macrophage polarization and suppressing the M1 phenotype.304 Copyright 2020, Elsevier