Fig. 9

Nanocomposite materials with M2 macrophage polarization-regulating properties. a Schematic illustration of Puerarin@Chitosan composite for tissue repair after bacterial infection. b Dexamethasone-loaded nanocomposites promoting the expression of the M2 macrophage marker CD206 and suppressing the expression of the M1 macrophage marker CCR7 in vitro (scale = 150 μm). Reproduced with permission from ref. 317 Copyright 2022, KeAi Publishing Communications Ltd. c Preparation and functional workflow of injectable hydrogel (GelMA/HAMA/BP@ZIF-8). d GelMA/HAMA/BP@ZIF-8 significantly suppressing the expression of the M1 macrophage marker iNOS while promoting the expression of the M2 macrophage marker CD206 in vitro (scale = 50 μm). Reproduced with permission from ref. 319 Copyright 2024, American Chemical Society