Table 2 mRNA expression of bone sialoprotein (BSP) in primary tumours and healthy tissue
From: Bone sialoprotein: a multifunctional regulator of bone remodelling and tumour progression
Cancer (Subtype) | mRNA expression of bone sialoprotein | Source (n) | Quantification | Reference | |
|---|---|---|---|---|---|
Normal (n) | Tumour (n) | ||||
Bone (OS) | + | +++* (85) | TARGET database | ||
Bone (OS) | –/o | +++* | Matched tissue (15) | ||
Brain | |||||
(HGG) (LGG) | ++ | +++*a (30) ++* (25) | Patients | RT-PCR | |
Brain (GBM) | ++ | +++NA | TCGA | ||
Breast | |||||
(Ductal) (Lobular) | o | +++* (31) + (31) | Matched tissue (53) | Cancer profiling array | |
Breast with bone MET and non-bone MET | +++ (6) | Patients | RNA sequencing | ||
Breast | +++ | GEPIA2 database | |||
Breast | +/++/+++ (18) | Patients | RT-PCR | ||
Colon | o | +++* | Matched tissue (39) | Cancer profiling array | |
Gastric (stomach) | o | +++* | Matched tissue (27) | Cancer profiling array | |
Kidney | o | ++* | Matched tissue (21) | Cancer profiling array | |
Bone marrow (MM) | ++/+++ (5) | In situ hybridisation | |||
Lung | o | +NS | Matched tissue (21) | Cancer profiling array | |
Lung | |||||
(LUAD) (LUSC) | o o | +++* +++* | TCGA | ||
Lung (LUAD) | 80% +/++/+++ (10) | Patients | RT-PCR | ||
Ovary | o | ++NS | Matched tissue (17) | Cancer profiling array | |
Pancreas (PDAC) | 41% o 59% – (27) | 86% +* (29) | Patients Organ donors | RT-PCR | |
Prostate | o | ++ | Matched tissue (4) | Cancer profiling array | |
Prostate | –/o | +++ (8) | Patients | In situ hybridisation | |
Rectum | o | +++* | Cancer profiling array | ||
Thyroid | o | ++* | Cancer profiling array | ||
Uterine (Endometrium) | o | +NS | Cancer profiling array | ||
