Fig. 8 | Bone Research

Fig. 8

From: Microenvironmental stiffness directs microtubule perturbation in chondrocyte mitosis via ILK-refilinB/Smad3 axis

Fig. 8

Schematic diagram indicating the role of ILK-refilin B/Smad3 axis in microenvironmental stiffness-mediated microtubule formation. Chondrocytes sense matrix stiffness and respond by altering the expression of interleukin ILK, a mechanically sensitive protein. ILK triggers changes in refilin B and the refilin B–Smad3 complex and regulates microtubule formation

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