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Antimicrobial resistance

Seriously risky antibiotics

Key points

  • Poor oral health can be life-threatening, and dentists are among the highest prescribers of antibiotics across human healthcare.

  • Antibiotics don't cure toothache, and they are associated with serious, life-threatening adverse outcomes, including Clostridioides difficile (C. diff) infection, anaphylaxis and antimicrobial resistance (AMR).

  • Prevention is better than cure. Universal access to oral healthcare is essential for preventing and treating acute oral and dental problems in line with clinical guidelines.

  • When people need antibiotics, they need them to work. Help keep antibiotics working by using them only when strictly necessary.

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Fig. 1

References

  1. British Dental Association. Dentists: skimping on urgent care risks fuelling antibiotic apocalypse. 2025. Available at https://www.bda.org/media-centre/dentists-skimping-on-urgent-care-risks-fuelling-antibiotic-apocalypse/ (accessed 1 November 2025).

  2. Peggy Lillis Foundation. Homepage. Available at https://cdiff.org/ (accessed 1 November 2025).

  3. GBD 2021 Antimicrobial Resistance Collaborators. Global burden of bacterial antimicrobial resistance 1990–2021: a systematic analysis with forecasts to 2050. Lancet 2024; 404: 1199–1226.

  4. The AMR Narrative. Founder. Available at https://amrnarrative.org/about-our-work/founder/ (accessed 1 November 2025).

  5. Royal College of Pathologists. National Medical Examiner's Good Practice Series No. 9. 2022. Available at https://www.rcpath.org_Good-Practice-Series-Recording-antimicrobial-resistance-on-the-Medical-Certificate-of-Cause-of-DeathFinal.pdf (accessed 1 November 2025).

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Correspondence to Wendy Thompson, Laurie Powell or Erick Venant.

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Thompson, W., Powell, L. & Venant, E. Seriously risky antibiotics. Br Dent J 239, 708–709 (2025). https://doi.org/10.1038/s41415-025-9381-0

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