Table 1 Baseline characteristics

From: Addition of intraperitoneal cisplatin and etoposide to first-line chemotherapy for advanced ovarian cancer: a randomised, phase 2 trial

Characteristic

IP/IV arm (N = 106)

IV arm (N = 109)

P valuea

Median age (range)

54 years

57 years

0.517

(35–78)

(40–75)

  

FIGO stage

  

0.706

 Stage IIIC

83 (78.3%)

83 (76.1%)

 

 Stage IV

23 (21.7%)

26 (23.9%)

 

Primary tumour

  

0.336

 Epithelial ovarian cancer

96 (90.6%)

99 (90.8%)

 

 Fallopian tube cancer

9 (8.5%)

6 (5.5%)

 

 Primary peritoneal cancer

1 (0.9%)

4 (3.7%)

 

Histology

  

0.537

 Serous

99 (93.4%)

101 (92.7%)

 

 Endometrioid

1 (0.9%)

2 (1.8%)

 

 Clear cell

1 (0.9%)

4 (3.7%)

 

 Undifferentiated

4 (3.8%)

2 (1.8%)

 

 Others

1 (0.9%)

0 (0%)

 

Grade

  

0.773

 Low

2 (1.9%)

3 (2.8%)

 

 High

104 (98.1%)

104 (95.4%)

 

 NA

0 (0%)

2 (1.8%)

 

ECOG performance status

  

0.580

 0

44 (41.5%)

40 (36.7%)

 

 1

58 (54.7%)

62 (56.9%)

 

 2

4 (3.8%)

7 (6.4%)

 

ASA Score

  

1.000

 1

62 (58.5%)

63 (57.8%)

 

 2

43 (40.6%)

46 (41.3%)

 

 3

1 (0.9%)

1 (0.9%)

 

Preoperative CA125 measurement

  

0.946

 Median serum level

870.5 U/ml

928.0 U/ml

 

 (range)

(13.6–25210.9)

(47.1–72090.3)

 

Ascites

  

0.186

 Median volume

1000 ml

800 ml

 

 (range)

(0–8000)

(0–7000)

 

Neoadjuvant chemotherapy

  

0.171

 Yes

14 (13.2%)

22 (20.2%)

 

 No

92 (86.8%)

87 (79.8%)

 

Residual disease in the whole abdomen

  

0.601

 0 cm

38 (35.8%)

40 (36.7%)

 

 0.1–0.5 cm

56 (52.8%)

52 (47.7%)

 

 0.5–1 cm

12 (11.3%)

17 (15.6%)

 
  1. ASA American Society of Anesthesiologists, ECOG Eastern Cooperative Oncology Group, FIGO International Federation of Gynecology and Obstetrics, NA not available.
  2. a Tested by χ2 or Mann–Whitney U-test